Cliques of Neurons Bound into Cavities Provide a Missing Link between Structure and Function

This week on Journal Club session Emil Dmitruk will talk about the paper "Cliques of Neurons Bound into Cavities Provide a Missing Link between Structure and Function".

The lack of a formal link between neural network structure and its emergent function has hampered our understanding of how the brain processes information. We have now come closer to describing such a link by taking the direction of synaptic transmission into account, constructing graphs of a network that reflect the direction of information flow, and analyzing these directed graphs using algebraic topology. Applying this approach to a local network of neurons in the neocortex revealed a remarkably intricate and previously unseen topology of synaptic connectivity. The synaptic network contains an abundance of cliques of neurons bound into cavities that guide the emergence of correlated activity. In response to stimuli, correlated activity binds synaptically connected neurons into functional cliques and cavities that evolve in a stereotypical sequence toward peak complexity. We propose that the brain processes stimuli by forming increasingly complex functional cliques and cavities.

Papers:


Date: 28/02/2020
Time: 16:00
Location: B200

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olfaction synaptic plasticity robotics machine learning Associative memory Purkinje cell Computer Science Neuromorphic hardware neural networks neuroscience Convolutional Neural Networks PCA Neuronal Morphology optimization Evolutionary algorithms Dendritic computation Persistent homology Deep learning computational modelling Open position cerebellum Neurons computational neuroscience Software development COVID-19 Network connectivity Studentship Homoeostasis Structural plasticity Artificial intelligence